Stage specific therapy

• Stage A1 - observation mostly, although some might advocate surgery
• Stages A2-B2 - the superiority of surgery or radiation has not been resolved.
• Stage A3- this stage represents the largest group of patients (no palpable disease, biopsied on the basis of PSA) treatment is not clear, but at least 30 percent of these patients have extensive disease.
• Stage C - often irradiated, although the appropriate therapy has not been determined.
• stage D1 - hormonal therapy or wait till symptomatic
• stage D2 -hormonal therapy